CMU Associate Professor Wen-Chin Huang Led an Academia-Industry Cooperation and Published Research Findings on the Journal Cancers
Date：June 18, 2020
A new hope for prostate cancer treatment! The academic-industry cooperation team led by China Medical University (CMU) Associate Professor Wen-Chin Huang discovered that the extract of Taiwan’s indigenous medicinal plant “Davallia formosana” exerts the effect of inhibiting the growth and metastasis of prostate cancer cells. This research finding “Emerging Therapeutic Activity of Davallia formosana on Prostate Cancer Cells through Coordinated Blockade of Lipogenesis and Androgen Receptor Expression” was published in the prestigious journal Cancers and has received great attention from the international medical community.
According to the latest statistics from the World Health Organization (WHO), cancer causes nearly ten million deaths a year worldwide. The occurrence of prostate cancer has been rising, and it is the fifth most common cancer among male patients in Taiwan. Currently, there is no effective way to cure patients with castration-resistant prostate cancer (CRPC).
The academic-industry cooperation team of Associate Professor Wen-Chin Huang, Associate Professor Guan-Jhong Huang, urologist Dr. Po-Fan Hsieh, and Dr. Wen-Ping Jiang investigated the function of the medicinal plant Davallia formosana. Through cell and animal experiments, they discovered that the extract of Davallia formosana has the effect of inhibiting the growth and metastasis of prostate cancer cells.
“We found that Davallia formosana can inhibit the growth (metastasis and invasion) of the androgen-dependent cell LNCaP and the hormone-refractory cell C4-2, which provides insights to the most challenging issue in prostate cancer research. Once we have the opportunity to perform clinical trials, this new discovery is likely to become a new complementary therapy for prostate cancer and benign prostatic hyperplasia. It will certainly bring new hope to the patients with prostate diseases,” said Associate Professor Wen-Chin Huang excitedly.