CMU Professor Jia-Zer Tsay Received the National Innovation Award by Discovering “A Novel Serological Test for Diagnosis of Rheumatoid Arthritis”

Date:September 24, 2019

Chinese Version

Breakthrough for the diagnosis of rheumatoid arthritis! Professor Jia-Zer Tsay, Director of Research and Development Center for Immunology, led his research team to discover a novel serological test for diagnosis of rheumatoid arthritis. This discovery enables patients to receive early diagnosis and treatment, which effectively reduces patients’ medical burden and helps improve their life quality. Professor Tsay’s research stands out from the competitors and was honored the 16th National Innovation Award.


About 20% of the world population are arthritis patients, while rheumatoid arthritis accounts for 1%. Currently, they are two major methods to diagnose rheumatoid arthritis: rheumatoid factor (RF), and antibodies against citrullinated protein antigens (ACPA). Unfortunately, at least 1/3 of the patients showed negative results for RF or ACPA. CMU Research and Development Center for Immunology led by Professor Tsay, discovered “A novel serological test for diagnosis of rheumatoid arthritis”. This novel test can effectively improve the rate of positive result (raise up from 54% to 80%) of rheumatoid arthritis patients.


“Rheumatoid arthritis is a chronic, destructive autoimmune disease that can only be diagnosed by clinical signs. If rheumatoid arthritis is not treated immediately, the patients’ condition might become aggravated and even disabled. Therefore, we developed this novel serological test, which not only improves the positive detection rate of clinical diagnosis, but also provides early treatment to patients that can effectively reduce the subsequent medical cost and improve their life quality.” said Professor Tsay.


The Research and Development Center for Immunology of China Medical University was established in 2015. It focuses on the research of the pathogenic mechanisms of autoimmune diseases, especially the role of protein citrullination, including diseases such as rheumatoid arthritis and lupus erythematosus. In addition, the center combined the basic experiences and the advantages of traditional Chinese medicine and Chinese herbal medicine, recruited Yushan scholar Dr. Monceg Zouali, and cooperated with the Genomic Research Center of Academia Sinica. By discovering novel herbal medicine, drugs, and peptides, and dedicating to the diagnosis and treatment of autoimmune diseases, the Research and Development Center for Immunology certainly enhance Taiwan’s research energy in the field of immunotherapy.


	Professor Jia-Zer Tsay's research team

Professor Jia-Zer Tsay's research team